Anti- EMG1 Antibody | FNab02754

Anti- EMG1 Antibody | FNab02754 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: S-adenosyl-L-methionine-dependent pseudouridine N (1) -methyltransferase that methylates pseudouridine at position 1248 (Psi1248) in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3- (3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Is not able to methylate uridine at this position (PubMed:20047967) . Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes (By similarity) .

Immunogen: EMG1 nucleolar protein homolog (S. cerevisiae)

synonyms: C2F

Molecular weight (observed) : 27 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IP, IF, FC

Recomended Dillution : WB: 1:500-1:2000; IF: 1:20-1:200

Research Area: Metabolism