Anti- FERMT3 Antibody | FNab03078

Anti- FERMT3 Antibody | FNab03078 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933) . Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity) . Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460) . Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity) . Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.

Immunogen: fermitin family homolog 3 (Drosophila)

synonyms: KIND3, MIG2B, URP2

Molecular weight (observed) : 72-76kd

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Research Area: Signal Transduction, Immunology