Anti-FKBP5 (FKBP51) monoclonal Antibody | MB62246

Anti-FKBP5 (FKBP51) monoclonal Antibody | MB62246 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, IHC, WB

Application Range: WB 1:2000, IHC 1:50, IF 1:100

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition.It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: FK506 binding protein 5

Molecular Weight: 51.2 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10

Immunogen: Full-length protein expressed in 293T cell transfected with human FKBP5 expression vector

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A