Anti- GM2A Antibody | FNab03518

Anti- GM2A Antibody | FNab03518 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 9C9

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity) . Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

Immunogen: GM2 ganglioside activator

synonyms: Ganglioside GM2 activator, GM2 AP, GM2 ganglioside activator, GM2A, SAP 3

Molecular weight (observed) : 22 kDa

Reactivity Species: Human

Tested Application: ELISA, IHC, WB, IP

Recomended Dillution : WB: 1:500-1:1000

Research Area: Metabolism