Anti-GPI (Glucose 6 phosphate isomerase) monoclonal Antibody | MB62260

Anti-GPI (Glucose 6 phosphate isomerase) monoclonal Antibody | MB62260 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:50

Background: This gene belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways. The protein encoded by this gene is a dimeric enzyme that catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: glucose-6-phosphate isomerase

Molecular Weight: 63 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: AMF; GNPI; NLK; PGI; PHI; SA-36; SA36

Immunogen: Full length human recombinant protein of human GPI (NP_000166) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A