Anti- GRB14 Antibody | FNab03641

Anti- GRB14 Antibody | FNab03641 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR) . Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Immunogen: growth factor receptor-bound protein 14

synonyms: N/A

Molecular weight (observed) : 61kd

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IHC

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Signal Transduction