Anti- Histone H2A.X Antibody | FNab03885

Anti- Histone H2A.X Antibody | FNab03885 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Immunogen: H2A histone family, member X

synonyms: H2A histone family, member X, H2A.X, H2A/X, H2AFX, H2AX, Histone H2A.x

Molecular weight (observed) : 16 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200

Research Area: Epigenetics, Metabolism, Developmental biology