Anti- Hsc70 Antibody | FNab09832

Anti- Hsc70 Antibody | FNab09832 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 4E11

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)

Immunogen: Hsc70

synonyms: Heat shock 70 kDa protein 8, heat shock 70kDa protein 8, HSC54, Hsc70, HSC71, HSP71, HSP73, HSPA10, HSPA8, LAP1, NIP71

Molecular weight (observed) : 70 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:3000-1:20000; IHC: 1:50-1:500

Research Area: Neuroscience, Cardiovascular, Metabolism