Anti-HSD17B10 monoclonal Antibody | MB62270

Anti-HSD17B10 monoclonal Antibody | MB62270 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:2000

Background: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD) . Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: hydroxysteroid (17-beta) dehydrogenase 10

Molecular Weight: 26.9 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD

Immunogen: Full-length protein expressed in 293T cell transfected with human HSD17B10 expression vector

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A