Anti- HSD3B7 Antibody | FNab04032

Anti- HSD3B7 Antibody | FNab04032 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C (19/21) steroids as substrates. Involved in bile acid synthesis (PubMed:11067870) . Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha, 25-dihydroxycholesterol (7-alpha, 25-OHC) : 7-alpha, 25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.

Immunogen: hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 7

synonyms: N/A

Molecular weight (observed) : 36 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Signal Transduction