Anti-HSPB1 (KO validated) Antibody | A2074

This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.

A2074 | Anti-HSPB1 (KO validated) Antibody DataSheet

Antibody Target: HSPB1

Target Alternative Name: HSPB1; CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27

Tag Line: Rabbit polyclonal knockout validated antibody to detect expression of HSPB1 in huma, mouse and rat samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Rat,Mouse,Human

Immunogen Sequence: Recombinant fusion protein targeting a sequence corresponding to aa 1-120 of human HSPB1

Accession #: P04792

Gene ID: 3315

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purified

Application: Immunohistochemistry (IHC),Immunofluorescence (IF),Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: False

Immunofluorescence Verified: True

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False