Anti- HTRA2 Antibody | FNab04070

Anti- HTRA2 Antibody | FNab04070 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

Immunogen: HtrA serine peptidase 2

synonyms: HtrA serine peptidase 2, HTRA2, OMI, PARK13, PRSS25, Serine protease 25, Serine proteinase OMI

Molecular weight (observed) : 36 kDa

Reactivity Species: Human, Mouse, Rat, Monkey

Tested Application: ELISA, WB, IF, IP, IHC

Recomended Dillution : WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200

Research Area: Neuroscience, Signal Transduction, Metabolism, Developmental biology