Anti-Human CD117 Monoclonal Antibody (FITC Conjugated) | DL21809F

Anti-Human CD117 Monoclonal Antibody (FITC Conjugated) | DL21809F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Mast/stem cell growth factor receptor Kit, Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117

Reactivity: Human

Application: FCM

Background: CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML) . CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.

Concentration: N/A

Conjugation: FITC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 104D2

Isotype: Mouse IgG1, κ