Anti-Human CD122/IL-3RB Monoclonal Antibody (APC Conjugated) | DL21814F

Anti-Human CD122/IL-3RB Monoclonal Antibody (APC Conjugated) | DL21814F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Interleukin-2 receptor subunit beta, IL-2RB, p75, CD122，IL-2Rβ

Reactivity: Human

Application: FCM

Background: CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.

Concentration: N/A

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: TU27

Isotype: Mouse IgG1, κ