Anti-Human CD39 Monoclonal Antibody (AF488 Conjugated) | DL21877F

Anti-Human CD39 Monoclonal Antibody (AF488 Conjugated) | DL21877F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: SPG64, NTPDase1, ATPDase, CD 39

Reactivity: Human

Application: FCM

Background: Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs) . CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details

Concentration: N/A

Conjugation: AF488

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: A1

Isotype: Mouse IgG1, κ