Anti-Human CD45RA Monoclonal Antibody (AF647 Conjugated) | DL20723F

Anti-Human CD45RA Monoclonal Antibody (AF647 Conjugated) | DL20723F | Gentaur UK, US & Europe Distribution

Host: Mouse

Synonyms: Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45

Reactivity: Human

Application: FCM

Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Concentration: N/A

Conjugation: AF647

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: HI100

Isotype: Mouse IgG2b, κ