Anti- ICAM-1 Antibody | FNab04103

Anti- ICAM-1 Antibody | FNab04103 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 7F11

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690) . ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056) . It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784) .

Immunogen: intercellular adhesion molecule 1

synonyms: BB2, CD54, ICAM 1, ICAM1, ICAM-1, P3.58

Molecular weight (observed) : 85-95 kDa

Reactivity Species: Human

Tested Application: ELISA, IF, WB, IHC, IP

Recomended Dillution : WB: 1:1000-1:4000; IHC: 1:50-1:500

Research Area: Stem Cells, Immunology, Cardiovascular