Anti- IDH1 Antibody | FNab04119

Anti- IDH1 Antibody | FNab04119 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 1G10

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer (PMID:15173171) .IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells (PMID:21079649 ) .

Immunogen: isocitrate dehydrogenase 1 (NADP+), soluble

synonyms: IDCD, IDH, IDH1, IDP, IDPC, NADP (+) specific ICDH, Oxalosuccinate decarboxylase, PICD

Molecular weight (observed) : 46kd

Reactivity Species: Human

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Research Area: Cancer, Metabolism