Anti- IL-4 Antibody | FNab04279

Anti- IL-4 Antibody | FNab04279 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 5A0

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Participates in at least several B-cell activation processes as well as of other cell types (PubMed:3016727) . It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity) .

Immunogen: interleukin 4

synonyms: B cell stimulatory factor 1, Binetrakin, BSF 1, BSF1, IL 4, IL4, IL-4, interleukin 4, PS1TP5BP1

Molecular weight (observed) : 18 kDa

Reactivity Species: Human, rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:5000; IHC: 1:20-1:200

Research Area: Immunology, Cardiovascular, Signal Transduction