Anti- IL1 Beta Antibody | FNab04210

Anti- IL1 Beta Antibody | FNab04210 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein G purified

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 9G5

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

Immunogen: interleukin 1, beta

synonyms: IL1 beta, Catabolin, IL 1, IL 1 beta, IL1 BETA, IL1B, IL1beta, IL1F2, IL-1β, Interleukin 1 beta, interleukin 1, beta

Molecular weight (observed) : 35kDa

Reactivity Species: Human

Tested Application: ELISA, IHC, WB

Recomended Dillution : WB: 1:1000-1:4000; IHC: 1:50-1:500

Research Area: Neuroscience, Immunology, Cardiovascular, Signal Transduction