Anti- IL10RB Antibody | FNab04215

Anti- IL10RB Antibody | FNab04215 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Immunogen: interleukin 10 receptor, beta

synonyms: CRFB4, D21S58, D21S66

Molecular weight (observed) : 42-45 kDa

Reactivity Species: Human

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:2000

Research Area: Immunology, Cardiovascular, Signal Transduction