Anti- IL1RL2 Antibody | FNab04246

Anti- IL1RL2 Antibody | FNab04246 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Receptor for interleukin-36 (IL36A, IL36B and IL36G) . After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity) . The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.

Immunogen: interleukin 1 receptor-like 2

synonyms: IL 1Rrp2, IL1R rp2, IL1RL2, IL1RRP2, interleukin 1 receptor like 2

Molecular weight (observed) : 65 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IF, IP

Recomended Dillution : WB: 1:500 - 1:1000

Research Area: Signal Transduction