Anti- IL22RA1 Antibody | FNab04253

Anti- IL22RA1 Antibody | FNab04253 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Immunogen: interleukin 22 receptor, alpha 1

synonyms: IL22R

Molecular weight (observed) : 62 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, FC

Recomended Dillution : WB: 1:500-1:2000; IF: 1:20-1:200

Research Area: Immunology, Cardiovascular, Signal Transduction