710
Anti- ITM2C Antibody | FNab04418
- SKU:
- 710-FNab04418-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- ITM2C Antibody | FNab04418 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity) .
Immunogen: integral membrane protein 2C
synonyms: BRI3
Molecular weight (observed) : 30 kDa
Reactivity Species: Human
Tested Application: ELISA, IHC
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200
Research Area: Neuroscience