Anti- KCNN4 Antibody | FNab04499

Anti- KCNN4 Antibody | FNab04499 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 8A11

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990) . Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin (PubMed:17157250, PubMed:18796614) .

Immunogen: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

synonyms: IK1, IKCA1, KCA4, SK4

Molecular weight (observed) : 48 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500 - 1:2000

Research Area: Neuroscience, Developmental biology