Anti-KDM4C monoclonal Antibody | MB62289

Anti-KDM4C monoclonal Antibody | MB62289 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Rat

Application: IF, IHC, WB

Application Range: WB 1:2000, IHC 1:50, IF 1:100

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: lysine demethylase 4C

Molecular Weight: 120.0 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GASC1; JHDM3C; JMJD2C; TDRD14C

Immunogen: Full-length protein expressed in 293T cell transfected with human KDM4C expression vector

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A