Anti- Lamin B1 Antibody | FNab04683

Anti- Lamin B1 Antibody | FNab04683 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 4A4

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This protein is not suitable for samples where the nuclear envelope has been removed.

Immunogen: lamin B1

synonyms: ADLD, lamin B1, LMN, LMN2, LMNB, LMNB1

Molecular weight (observed) : 66kd

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC, IF, WB

Recomended Dillution : WB: 1:500-1:2000; IP: 1:5000-1:50000 ; IHC: 1:500-1:2000; IF: 1:50-1:500

Research Area: Stem Cells, Developmental biology