Anti- LGI1 Antibody | FNab04760

Anti- LGI1 Antibody | FNab04760 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity) . Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.

Immunogen: leucine-rich, glioma inactivated 1

synonyms: EPT

Molecular weight (observed) : 64 kDa, 58 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP, IF

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:200

Research Area: Neuroscience, Developmental biology