Anti- LINGO1 Antibody | FNab04792

Anti- LINGO1 Antibody | FNab04792 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321) . Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088) . Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity) .

Immunogen: leucine rich repeat and Ig domain containing 1

synonyms: LERN1, LRRN6A

Molecular weight (observed) : 83 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IP

Recomended Dillution : WB: 1:500-1:2000

Research Area: Neuroscience, Stem Cells, Signal Transduction, Developmental biology