Anti- MCM2 Antibody | FNab05057

Anti- MCM2 Antibody | FNab05057 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 4E3

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

Immunogen: minichromosome maintenance complex component 2

synonyms: BM28, CCNL1, CDCL1, KIAA0030

Molecular weight (observed) : 116-125 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:1000-1:2000

Research Area: Epigenetics, Cancer, Immunology, Metabolism