Anti-MME Antibody (Clone# MME/1892) | A2234

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.

A2234 | Anti-MME Antibody (Clone# MME/1892) DataSheet

Antibody Target: MME

Target Alternative Name: NEP, SFE, CD10, CALLA, CMT2T, SCA43, Atriopeptidase, Neprilysin, gp100

Tag Line: Mouse monoclonal antibody to detect the expression of Membrane metalloendopeptidase in human samples

Category: Primary antibody

Host: Mouse

Isotype: IgG2c, kappa

Species Reactivities: Human

Immunogen Sequence: Recombinant human CD10 protein fragment (aa 297-483)

Accession #: P08473

Gene ID: 4311

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 10 mM PBS

Purification: Protein A/G purified

Application: Immunohistochemistry (IHC),Western Blotting

Positive Control:

Application And Usages: WB (1-2 µg/ml), IHC (1-2 µg/ml)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE