710
Anti- MMP13 Antibody | FNab05235
- SKU:
- 710-FNab05235-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- MMP13 Antibody | FNab05235 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.It can detect the glycosylated proMMP-13 (70 kDa), unglycosylated proform (54 kDa) .
Immunogen: matrix metallopeptidase 13 (collagenase 3)
synonyms: CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13
Molecular weight (observed) : 54kd, 70kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recomended Dillution : WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Research Area: Stem Cells, Cardiovascular, Metabolism