Anti- MMP14 Antibody | FNab05236

Anti- MMP14 Antibody | FNab05236 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Immunogen: matrix metallopeptidase 14 (membrane-inserted)

synonyms: MMP-14

Molecular weight (observed) : 65 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, IF

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction