Anti- MNAT1 Antibody | FNab05252

Anti- MNAT1 Antibody | FNab05252 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.

Immunogen: menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)

synonyms: CAP35, MAT1, RNF66

Molecular weight (observed) : 36 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC

Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200

Research Area: Cell Division and Proliferation, Metabolism