Anti-Mouse CD183/CXCR3 Monoclonal Antibody (APC Conjugated) | DL21404F

Anti-Mouse CD183/CXCR3 Monoclonal Antibody (APC Conjugated) | DL21404F | Gentaur UK, US & Europe Distribution

Host: Armenian Hamster

Synonyms: C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183/CXCR3

Reactivity: Mouse

Application: FCM

Background: CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4) . CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Concentration: 0.2 mg/mL

Conjugation: APC

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: CXCR3-173

Isotype: Armenian Hamster IgG