Anti-Mouse CD209b Monoclonal Antibody (Biotin Conjugated) | DL20385F

Anti-Mouse CD209b Monoclonal Antibody (Biotin Conjugated) | DL20385F | Gentaur UK, US & Europe Distribution

Host: Armenian Hamster

Synonyms: CD209 antigen-like protein B, Cd209b, DC-SIGN-related protein 1, DC-SIGNR1, OtB7, CD209, Cd209b

Reactivity: Mouse

Application: FCM

Background: CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Concentration: 0.5 mg/mL

Conjugation: Biotin

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: 22D1

Isotype: Armenian Hamster IgG