Anti-Mouse IL-10 Monoclonal Antibody (PE Conjugated) | DL22152F

Anti-Mouse IL-10 Monoclonal Antibody (PE Conjugated) | DL22152F | Gentaur UK, US & Europe Distribution

Host: Rat

Synonyms: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF

Reactivity: Mouse

Application: ICFCM

Background: L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production) ; and promotes mast cell proliferation in combination with IL-4.

Concentration: N/A

Conjugation: PE

Buffer: PBS with 0.05% Proclin300, 1% BSA

Clone: JES5-16E3

Isotype: Rat IgG2b, κ