Anti-Nectin-4 Antibody | A2283

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

A2283 | Anti-Nectin-4 Antibody DataSheet

Antibody Target: Nectin-4

Target Alternative Name: LNIR, PRR4, EDSS1, PVRL4, nectin-4, NECTIN4, Nectin 4

Tag Line: Rabbit polyclonal antibody to detect Nectin-4 expression in human and mouse samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Human, Mouse

Immunogen Sequence: Recombinant Human Nectin-4 protein

Accession #: Q96NY8

Gene ID: 81607

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300

Purification: Protein G purified

Application: Immunohistochemistry (IHC) Immunofluorescence (IF) Western Blotting

Positive Control:

Application And Usages: WB (1:500-1:5000), IHC (1:200-1:500), IF (1:50-1:200)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: TRUE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: TRUE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE