Anti- NF-L Antibody | FNab05710

Anti- NF-L Antibody | FNab05710 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Immunogen: neurofilament, light polypeptide

synonyms: 68 kDa neurofilament protein, CMT1F, CMT2E, FLJ53642, NEFL, NF L, NF68, NFL

Molecular weight (observed) : 72 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:200

Research Area: Neuroscience, Stem Cells, Immunology