Anti-NS1 of Dengue Virus, Humanized Antibody | A2297

The mosquito-borne Dengue viruses (serotype 1-4) cause dengue fever, a severe flu-like illness. The disease is prevalent in Third World tropical regions, and continues to spread to sub-tropical developed countries, as well the United States. The Dengue viral genome consists of a single-stranded RNA that encodes a single polyprotein. The Dengue genome polyprotein, upon translation, is then co- and post-translationally cleaved into 11 mature proteins, including the non-structural protein NS1. Dengue NS1 has been implicated in the viral immune evasion ability by antagonizing complement function as well as inhibiting Toll-like receptor 3 signal transduction. This research-grade biosimilar is a humanized antibody that targets the Dengue NS1 protein.

A2297 | Anti-NS1 of Dengue Virus, Humanized Antibody DataSheet

Antibody Target: NS1 protein portion of Dengue virus genome polyprotein

Target Alternative Name: Non-structural protein 1

Tag Line: A humanized monoclonal antibody that targets Dengue virus NS1 protein

Category: GM-CSF

Host: CHO cells

Isotype: IgG1

Species Reactivities: Dengue virus

Immunogen Sequence: FALSE

Accession #: Q99D35

Gene ID: 5075727

Appearance: Liquid

Form: Humanized IgG1

Concentration:

Formulation: In PBS, pH 7.5

Purification: FALSE

Application: FALSE

Positive Control:

Application And Usages:

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified:

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified:

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE