Anti- NT5E/CD73 Antibody | FNab05878

Anti- NT5E/CD73 Antibody | FNab05878 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: NT5E (5'-nucleotidase) is also named as NT5, NTE, CD73, ecto-5'-nucleotidase, and belongs to the 5'-nucleotidase family. It catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.The enzyme occurs mainly as a dimer and the wide distribution of NT5E in the rat hippocampus, suggesting their involvement in the control of the purinergic signaling (PMID:17619139) . This protein has two isoforms with the molecular weight of 63 kDa and 58 kDa and four glycosylation sites with a signalpeptide. It can exsit as a dimer (PMID:17619139) . It can be detected the band of 55 kDa, 64 kDa, 70 kDa, 110 kDa by western blot (PMID:17619139; 12370277; 21533188) . Defects in NT5E are the cause of calcification of joints and arteries (CALJA) .

Immunogen: 5'-nucleotidase, ecto (CD73)

synonyms: 5 NT, 5 nucleotidase, 5' nucleotidase, ecto (CD73), CD73, E5NT, Ecto 5 nucleotidase, eN, eNT, NT, NT5, NT5E, NTE

Molecular weight (observed) : 63 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:5000; IHC: 1:50-1:500

Research Area: Metabolism, Cardiovascular, Immunology, Cancer, Stem Cells