Anti-NTRK2 (TrkB ) monoclonal Antibody | MB62337

Anti-NTRK2 (TrkB ) monoclonal Antibody | MB62337 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, IHC, WB

Application Range: WB 1:1000, IHC 1:150, IF 1:100

Background: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: neurotrophic receptor tyrosine kinase 2

Molecular Weight: 92 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GP145-TrkB; trk-B; TRKB

Immunogen: Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A