Anti-NTRK3 (TrkC) monoclonal Antibody | MB62339

Anti-NTRK3 (TrkC) monoclonal Antibody | MB62339 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IHC, WB

Application Range: WB 1:2000, IHC 1:50

Background: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: neurotrophic receptor tyrosine kinase 3

Molecular Weight: 94.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: GP145-TrkC; TRKC; gp145 (trkC)

Immunogen: Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A