Anti- OCRL Antibody | FNab05959

Anti- OCRL Antibody | FNab05959 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate and inositol 1, 3, 4, 5-tetrakisphosphate to inositol 1, 3, 4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698) . May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4, 5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976) .

Immunogen: oculocerebrorenal syndrome of Lowe

synonyms: INPP5F, OCRL1

Molecular weight (observed) : 105 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC, IF, IP, WB

Recomended Dillution : WB: 1:500-1:2000

Research Area: Neuroscience, Signal Transduction, Metabolism