Anti- ORAI1 Antibody | FNab06002

Anti- ORAI1 Antibody | FNab06002 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 8C0

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Ca (2+) release-activated Ca (2+) (CRAC) channel subunit which mediates Ca (2+) influx following depletion of intracellular Ca (2+) stores and channel activation by the Ca (2+) sensor, STIM1. CRAC channels are the main pathway for Ca (2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901) .

Immunogen: ORAI calcium release-activated calcium modulator 1

synonyms: CRACM1, FLJ14466, ORAI1, ORAI1 L1, ORAI1 L2, Orail L2, ORAT1, Protein orai 1, TMEM142A, Transmembrane protein 142A

Molecular weight (observed) : 32 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IF

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:50-1:500

Research Area: Immunology, Signal Transduction