Anti-p504s/AMACR Rabbit Monoclonal Antibody (RM349) | A1848

It is an enzyme that is involved in bile acid biosynthesis and ?-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.

A1848 | Anti-p504s/AMACR Rabbit Monoclonal Antibody (RM349) DataSheet

Antibody Target: p504s/AMACR (Alpha-methylacyl-CoA racemase)

Target Alternative Name:

Tag Line: Affinity purified Rabbit monoclonal to p504s/AMACR (Alpha-methylacyl-CoA racemase)

Category: Primary antibody

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: A peptide corresponding to the N-terminus of human Alpha-methylacyl-CoA racemase.

Accession #: Q9UHK6

Gene ID: 23600

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Protein A affinity purified from an animal origin–free culture supernatant

Application: Western Blot: 1:1000-1:2000, IHC: 1:500-1:1000

Positive Control:

Application And Usages: Western Blot: 1:1000-1:2000, IHC: 1:500-1:1000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: True

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False