Anti- P62/SQSTM1 Antibody | FNab09853

Anti- P62/SQSTM1 Antibody | FNab09853 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: protein A+G purified

Purity: ≥95% as determined by SDS-PAGE

Host: mouse

Clonality: monoclonal

Clone ID: 5H3

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Immunogen: sequestosome 1

synonyms: P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62

Molecular weight (observed) : 62 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC, IF, IP

Recomended Dillution : WB: 1:1000 - 1:4000; IHC: 1:50 - 1:500; IF: 1:20 - 1:200

Research Area: Neuroscience, Cardiovascular, Metabolism, Signal Transduction