Anti-PAD2 Monoclonal Antibody (Clone 9F7) | A2312

Protein arginine deiminases (PADs) are a family of guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD2 is the most widely expressed and evolutionarily conserved family member. Known substrates for PAD2 include myelin basic protein and vimentin, and PAD2 is thought to play a role in the onset and progression of neurodegenerative diseases such as Alzheimer's and multiple sclerosis. PAD2 may also play a role in transcriptional regulation as it is capable of citrullinating histone H3.

A2312 | Anti-PAD2 Monoclonal Antibody (Clone 9F7) DataSheet

Antibody Target: Human PAD2

Target Alternative Name: Peptidyl Arginine Deiminase 2; PDI2; Protein-Arginine Deiminase Type II; EC 3.5.3.15; KIAA0994; PAD-H19; PADI2

Tag Line: Potentially involved in autoimmune diseases

Category: GM-CSF

Host: Mouse

Isotype: Mouse IgG1

Species Reactivities: Human

Immunogen Sequence: Full length recombinant human PAD2 protein

Accession #: Q9Y2J8

Gene ID: 11240

Appearance: Liquid

Form: Mouse monoclonal

Concentration:

Formulation: In PBS, pH 7.2, 50% glycerol, 0.1% BSA, 0.02% sodium azide

Purification: Protein G purification

Application: Western Blotting Immunohistochemistry (IHC)

Positive Control:

Application And Usages:

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: TRUE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE