Anti-PAD6 Monoclonal Antibody (Clone 4B7) | A2315

Protein arginine deiminases (PADs) are a family of guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD6 is primarily expressed in mammalian oocytes, sperm cells, and early embryoes. PAD6 may have a role in regulating microtubule-mediated organelle mobility and positioning within cells, and cytoskeletal reorganization in the egg and early embryo. Dysregulation of PAD6 is associated with embryonic lethality.

A2315 | Anti-PAD6 Monoclonal Antibody (Clone 4B7) DataSheet

Antibody Target: Human PAD6

Target Alternative Name: Peptidyl Arginine Deiminase 6; Peptidyl Arginine Deiminase-Like Protein; Peptidyl Arginine Deiminase, Type VI; Protein-Arginine Deiminase Type-6; EC 3.5.3.15; HPADVI; Protein-Arginine Deiminase Type VI; Peptidylarginine Deiminase Type 6; Peptidylarginine Deiminase VI; PREMBL2; PADI6

Tag Line: Protein arginine deiminase associated with embryonic development

Category: GM-CSF

Host: Mouse

Isotype: Mouse IgG1

Species Reactivities: Human

Immunogen Sequence: Full-length human recombinant PAD6 protein

Accession #: Q6TGC4

Gene ID: 353238

Appearance: Liquid

Form: Mouse monoclonal

Concentration:

Formulation: In PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide

Purification: Protein G purification

Application: Western Blotting

Positive Control:

Application And Usages:

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE