Anti- PAG1 Antibody | FNab06112

Anti- PAG1 Antibody | FNab06112 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Immunogen: phosphoprotein associated with glycosphingolipid microdomains 1

synonyms: CBP, PAG

Molecular weight (observed) : 50-60 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:500-1:2000

Research Area: Immunology, Signal Transduction